New inhibitors of VEGFR-2 targeting the extracellular domain dimerization process
نویسندگان
چکیده
منابع مشابه
New inhibitors of VEGFR-2 targeting the extracellular domain dimerization process
We are reporting the discovery of small molecule inhibitors for vascular endothelial growth factor receptor type 2 (VEGFR-2) extracellular domain. The VEGFR-2 extracellular domain is responsible for the homo-dimerization process, which has been recently reported as a main step in VEGFR signal transduction cascade. This cascade is essential for the vascularization and survival of most types of c...
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ژورنال
عنوان ژورنال: Bioinformation
سال: 2011
ISSN: 0973-8894,0973-2063
DOI: 10.6026/97320630007052